Mlb Opening Day 2025 Date. The mlb winter meetings, the much larger annual baseball industry gathering, will take place dec. The mlb announced in august that the los angeles dodgers and chicago cubs will open 2025 spring training on thursday, february 20.

Detroit’s biggest party, opening day, presented by rocket mortgage, is slated for friday, april 4 against the chicago white sox. From the tokyo series and opening day through the end of the regular season, here are the key dates to know on the 2025 mlb schedule.